Home Project MilliporeSigma

Project Overview

Heffron has delivered mechanical scope across MilliporeSigma’s Maryland life sciences operations, tying new equipment into live research and manufacturing environments without interrupting production.

The work spans the full utility backbone of the site — from rooftop heat rejection down through the central plant and out to validated process rooms — keeping cooling, high-purity water, and clean utilities reliable for sensitive research and biomanufacturing workloads.

Heffron continues to service the building today. What started as a build relationship is now an ongoing service partnership — the same crews who installed the cooling towers, chillers, high-purity water systems, and central plant equipment are back on site keeping it running years later. That’s the Heffron model: build it right the first time, then stay with the client to maintain it for the life of the facility.

Scope of Work

01

Rooftop cooling towers and condenser water — evaporative cooling towers set by crane, with adjacent air handlers and ductwork reworked to suit the new heat-rejection layout.

02

Chilled water distribution — primary chilled water and CHW return piping routed through the facility and tied into mechanical room equipment and controls.

03

High-purity and process water systems — multi-vessel filtration, softening, and DI trains, plus skid-mounted process water packages with PLC-driven controls feeding lab and production points of use.

04

Central utility plant — pressure vessels, expansion and storage tanks, heat exchangers, and hot-water generation, installed and tied into existing site utilities.

05

Cleanroom process equipment — stainless steel pass-through autoclave set and connected to steam, water, drain, and exhaust within a validated cleanroom envelope.

06

Mechanical service and detail work — overhead piping, valve stations, and utility-corridor build-out supporting the broader scope.

07

Ongoing service — Heffron's service division continues to maintain the facility today, the same team that built it.

Project Details

Client

MilliporeSigma

Location

Maryland

Sector

Life Sciences

Engagement

Build + ongoing service — Heffron still services the building today

Project Gallery

On-site at United Therapeutics GMP Therapy Production Facility.

United Therapeutics United Therapeutics — view 2

Project Gallery

On-site at MilliporeSigma.

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Heffron self-performs mechanical construction across the DMV — Washington D.C., Maryland, and Virginia — including inside active, validated production facilities.